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In contrast, excessive or unregulated ROS production can compromise mitochondrial membrane potential, trigger cytochrome c (Cyt c) release, and induce oocyte apoptosis through the Bax/Bak-dependent mitochondrial apoptotic pathway, potentially leading to follicular atresia or depletion of the ovarian reserve [34, 35]

Nevertheless, vigorous agitation can increase foam, interfaces, and physical instability

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Pericytes are also involved in the formation of the basement membrane (BM) and the removal of toxic metabolites and inflammatory mediators (Rust et al., 2025)

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N-Nitrosodiethylamine and carcinogenicity: an over review